Blog, Resource, & Helpline for those battling Percocet addiction

Mixing Percocet with Addictive Substances

Simply put, Percocet is morphine in pill form. It affects the central nervous system, thus slowing down a person’s breathing, creating the euphoric feeling many become addicted to. Over time, both the body and mind become accustomed to it and addiction occurs. When mixed with other substances, the effects are intensified as are the risks. The period of “coming down” after taking a combination of Percocet and another substance is stronger also which means an individual will likely need to continue taking both together to recreate the high. Consequently, death has a stronger likelihood of occurring.

Percocet and Alcohol

Percocet’s main ingredient, oxycodone is combined with acetaminophen, which heightens the effects of oxycodone in a person’s system. Most importantly, the use of oxycodone medications of any form in combination with alcohol-based drinks goes completely against medical advice. These medications intensify the side effects of central nervous system and respiratory depression. Both alcohol and Percocet decrease breathing. Thus, when mixed they are extremely dangerous especially if you have breathing related difficulties already. Also, the combination of alcohol and opioid narcotics significantly increased the probability of psychological addiction to both the medication and the alcohol. The extended use of any opioid narcotic will result in some level of physiologic dependence, though the amount of dependence is different with each patient.

The acetaminophen can also become a toxin for the liver when combined with any drink of alcohol. Taking any kind of pain medication in close proximity to alcohol is a leading cause of sudden liver failure in otherwise healthy middle-age adults. They might exaggerate the sedative effect (depending on the amounts) which could lead to a dangerous loss of consciousness. Let your doctor know if you consume three or more alcoholic beverages per day or if you have ever been diagnosed with alcoholic liver disease, or cirrhosis. It is likely you will not be permitted to take medications containing acetaminophen.

Percocet and Ibuprofen

Ibuprofen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ibuprofen works by reducing hormones that cause inflammation and pain in the body. The combination of ibuprofen and oxycodone (main ingredient in Percocet) is used short-term to relieve moderate to severe pain. Ibuprofen can increase your risk of heart attack or stroke. It can also increase your risk of serious effects on the stomach or intestines. These conditions can be fatal and can occur without warning at any time while you are taking ibuprofen. Before using ibuprofen and oxycodone, tell your doctor if you have:

  • Heart disease
  • Congestive heart failure
  • High blood pressure or a history of heart attack, stroke, or blood clot
  • Asthma or other breathing disorders
  • Liver or kidney disease
  • A history of head injury or brain tumor
  • Epilepsy or other seizure disorder
  • Stomach or intestinal disorder
  • History of stomach ulcer or bleeding
  • Underactive thyroid
  • Pancreas disorder
  • Addison’s disease or other adrenal gland disorder
  • Curvature of the spine
  • An enlarged prostate or problems with urination
  • Mental illness
  • History of drug or alcohol addiction

If you have any of these conditions, you may need a dose adjustment or special tests to safely take ibuprofen and oxycodone.

Since oxycodone is a painkiller, it is dangerous to combine it with over-the-counter pain relievers, cold and flu remedies, allergy medications, sleep aids, and even some herbal dietary supplements. This is particularly true of the Percocet combination, since they already contain over-the-counter pain relievers like acetaminophen. Overdose of aspirin and acetaminophen can be life-threatening.

Percocet and Other Drug Combinations

Percocet side effects can cause drowsiness and slows breathing, so it should not be combined with antidepressants, antihistamines (allergy ingredients), anti-anxiety drugs, prescription sleeping pills or muscle relaxants.

Emergency room visits for drug overdose often involve more than one substance. Needless to say, it is highly dangerous to mix oxycodone with any illegal drug, including marijuana, cocaine, hallucinogens such as LSD, ecstasy, or especially heroin.

If Percocet is taken with certain other drugs, the effects of either could be increased, decreased or altered. It is especially important to check with your doctor before combining Percocet with the following:

  • Antispasmodic drugs
  • Major tranquilizers
  • Other narcotic painkillers
  • Sedatives such as phenobarbital
  • Tranquilizers

If you are taking any of these medications, legal or otherwise, speak with your doctor or pharmacist about it. Depending on your individual circumstances, your healthcare provider may want you to either: stop taking one or more of the medications; substitute one medication for another; change how you are taking one or both of the medications; or maintain your current routine. The severity of risks varies from person to person. Watch this Percocet Abuse Video.

Percocet Help

If you or someone you know is struggling with a Percocet addiction, please know that Percocet abuse help is available. You can call our toll free number at (866) 872-6492 and get all your questions about addiction and treatment answered.